In an unbiased expression analysis of GNA12 mRNA expression across 32 different cancers, we found that eight tumors, including DLBCL, esophageal carcinoma, glioblastoma multiforme, head and neck squamous cell carcinoma (HNSCC), brain low-grade glioma, pancreatic adenocarcinoma, skin cutaneous melanoma, and thymoma, showed significant increases in GNA12 mRNA compared to their corresponding normal tissues, further confirming the implication of Gα12 in cancer (Table 1). The gene discussed is GNA12; the disease is head and neck squamous cell carcinoma.