As Li et al. previously reported that miR-142-5p targeted MCL1 and other multiple antiapoptotic genes, and enhanced cisplatin-induced apoptosis in ovarian cancer cells [18]; and Su J et al. showed that NF1 could target MCL1 via miR-142-5p to regulate apoptosis in ovarian cancer cells [19]; so we speculated that miR-142-5p could regulate OS chemoresistance by affecting the expression of the antiapoptotic protein, MCL1, a member of the Bcl-2 family. This evidence concerns the gene NF1 and ovarian cancer.