Moreover, the correlations between the expression of LSD1 (KDM1A) and immune signature genes such as CD8+ T cell-attracting chemokines (CCL5, CXCL9, CXCL10, CXCR3, CXCR4, CXCR6, and CXCR8) and the immune checkpoint molecule PDL1 (CD274) were evaluated in a cohort of HNSCC clinical specimens in The Cancer Genome Atlas. This evidence concerns the gene CXCR4 and head and neck squamous cell carcinoma.