In addition, sintilimab (Tyvyt®), also a monoclonal antibody against PD-1, which works by blocking the association between PD-1 and its ligands, has been approved by the National Medical Products Administration (NMPA) of China to treat relapsed or refractory classical Hodgkin lymphoma in patients refractory to two or more lines of systemic chemotherapy [14]. This evidence concerns the gene PDCD1 and Hodgkins lymphoma.