Interestingly, these two patient subgroups exhibited different correlation patterns between the levels of miR-137 and COX6A2: high miR-137 exosomal concentrations were associated with low exosomal COX6A2 protein levels in Psy-D but not in Psy-ND or in control subjects (Fig. 3Ae). This evidence concerns the gene COX6A2 and Norrie disease.