Using female rats that express the human variant of the pancreatic hormone amylin specifically in the β-cells (HIP rats) as a GDM model and their WT littermates as controls, we found here that pathological cardiac hypertrophy is also present two months post-delivery in female rats with GDM-complicated pregnancies but not in females with normal pregnancies (Fig. 2). The gene discussed is IAPP; the disease is gestational diabetes.