To determine whether the PDGFRB-STAT3 pathway is activated in liver cancer-induced fibrosis, tumor and the adjacent normal liver tissues resected from subjects with liver fibrosis, which was caused by hepatocellular carcinoma (HCC) or cholangiocarcinoma (CCC), were immunostained with PDGFRB and pSTAT3 antibodies. The gene discussed is STAT3; the disease is Hepatic fibrosis.