In addition, exosomes isolated from gastric carcinoma cells are rich in miR-106a and are delivered to the peritoneal mesothelial cells by horizontal transfer, which further regulates the apoptotic and migration ability of gastric carcinoma cells by mediating the processing of EMT through targeting Smad7 and finally contributes to the development of peritoneal metastasis [16]. The gene discussed is SMAD7; the disease is gastric carcinoma.