We demonstrated this by running MINTIE on a cohort of 87 B-ALL samples, where we found interesting events in disease relevant genes, including 3 samples with the same RB1 unpartnered fusion, IKZF1 and PAX5 PTDs, and 2 samples with altered splicing of ETV6. Here, ETV6 is linked to precursor B-cell acute lymphoblastic leukemia.