The combination of 0.8 mg/kg BD0801 and 5 mg/kg anti-PD-1 antibody showed statistically better tumor growth inhibition compared to both single treatments (P < 0.05, T/C 44.4% for 0.8 mg/kg BD0801, T/C 54.2% for 5 mg/kg anti-PD-1 antibody, T/C 23.6% for combination, Fig. 3C). This evidence concerns the gene PDCD1 and neoplasm.