In contrast, the combination of 2.5 mg/kg BD0801 and 10 mg/kg anti-PD-1 antibody significantly reduced tumor growth, with a T/C of 46.8% (Fig. 5B), as well as the combination of 2.5 mg/kg BD0801 and 5 mg/kg anti-PD-L1 antibody, with a T/C of 31.3% (Fig. 5C). This evidence concerns the gene PDCD1 and neoplasm.