First, cells from a patient with cystic fibrosis are isolated and manipulated in the laboratory to reprogramme them into iPSCs; then, the CFTR mutation is converted to the wildtype status, and finally, the corrected iPSCs are turned into basal airway stem cells which have the capacity to differentiate into all cell types of pseudostratified airway epithelium [46]. Here, CFTR is linked to cystic fibrosis.