To examine ChREBP-dependent response on metabolic processes and thus on hepatocarcinogenesis progression, we next performed RNA sequencing-based transcriptional profiling on tissues derived from liver tumor (tumor formed in 12 months) of knock-out as well as corresponding wild type mice, and compared them in between and also with the non-tumorous control tissue obtained from same mouse liver. This evidence concerns the gene MLXIPL and neoplasm.