Of a total of 17,467 genes, around 1777 genes were significantly upregulated by at least 1.5-fold (FDR < 0.05 and fold-change >= 1.5) in wild type tumor, whereas downregulated expression was noticed in 1222 genes in tumor that lacked ChREBP (supplementary Figure S8, group A_C). The gene discussed is MLXIPL; the disease is neoplasm.