Similarly to TB, but on a smaller magnitude, patients with active sarcoidosis had significantly higher blood levels of NPC2 in comparison with control (p < 0.0001), which was not observed for any of the other disease groups (Figure 3C, control vs. non-active sarcoidosis: 0.07, vs. lung cancer: 0.052, vs. pneumonia > 0.99). Here, NPC2 is linked to susceptibility to pneumonia measurement.