The massive increase of number of CD8+ T cells (Figure 1c) was associated with significantly higher frequency of CD8+ T expressing activation marker CD69 in the AIH untreated group compared to Normal group (76.6 ± 3.9 vs. 42.6 ± 2.1% of CD69+ cells per CD8+ T cells, p = 0.0020, Figure 1e). This evidence concerns the gene CD69 and autoimmune hepatitis.