Furthermore, the overexpression of NDRG2 and p53 was shown to enhance the apoptosis of Huh7 cells (mutant p53) after Adriamycin-based chemotherapy and suppress the expression of the ERCC6 gene [56], which is involved in a sub-pathway of nucleotide excision repair and is associated with cancer drug resistance [57,58]. Here, NDRG2 is linked to cancer.