Interestingly, treatment with BMP-7 attenuated the increased expression of Nek7 (Figure 2G, p = 0.038) and GBP5 (Figure 2H, p = 0.01) compared to the diabetic group, suggesting that BMP-7 attenuates inflammasome protein regulators Nek7 and GBP5 prior to the initiation of NLRP3 upregulation in diabetic cardiomyopathy. The gene discussed is GBP5; the disease is diabetic cardiomyopathy.