Diabetic cardiomyopathy involves multiple pathophysiological changes such as downregulation of glucose transporter type-4 (GLUT4) recruitment, decrease in nitric oxide, increased reactive oxidative stress (ROS), collagen deposition/fibrosis, cell deaths (apoptosis, necrosis, and autophagy), and inflammation [2,3]. This evidence concerns the gene SLC2A4 and diabetic cardiomyopathy.