In this sense, studies have shown that exosomes produced and released by cancer cells contain various biomolecules, including nuclear factor kappa B (NFκB) and signal transducer activator of transcriptions 3 (STAT3), as well as inflammatory cytokines, such as interleukin (1L)-1β, -6, and tumor necrosis factor-alpha (TNF-α), which promotes the recruitment of immune cells to target sites as revisited by Othman et al. [50]. The gene discussed is TNF; the disease is cancer.