Therefore, we examined the possible correlation of key cytokines (IL-1β, TNF-α, IL-4, and IL-6) known to drive crosstalk between KCs and immune sentinels, which results in psoriasis development [27,28], with the induction of miR-21-5p or miR-21-3p expression (Figure S3). The gene discussed is TNF; the disease is psoriasis.