NDG from severe/critical COVID-19 patients may be primed in vivo to spontaneously produce NETs, since they are exposed to IL-6, IL-2, IL-7, TNF, CXCL10, MCP-1, MIP1a [40], GM-CSF and M-CSF during the cytokine storm [41]. This evidence concerns the gene CXCL10 and COVID-19.