AB-118 and NIK-67 [30] were assayed as inhibitors of a panel of human CAs, which are isoforms of the ubiquitous, cytosolic and off-target CAs I and II, the membrane-bound and target CA IV and the transmembrane tumour-associated CA IX, using a stopped-flow CO2 hydrase assay (Table 1). This evidence concerns the gene CA9 and neoplasm.