MAPT and Alzheimer disease: Using positron emission tomography (PET) to detect cerebral tau deposition (F-18 Tau-AD-ML 104) and glucose metabolism (F-18 FDG), Baghel and colleagues recently showed that tau pathology overlaps with glucose hypometabolism in the brain of AD patients, namely in the parietal lobe, temporal lobe, hippocampus, parahippocampus, frontal lobe, anterior and posterior cingulate, and precuneus [33].