Finally, since autophagosomes are known to contain ATP immunostimulatory molecules, as well as several proteins acting to alarm the immune system [116], autophagy induction in ALK+ ALCL cells and the release of their autophagosome content in the tumor microenvironment could potentially contribute to the immunogenic cell death (ICD) of the lymphoma cells. The gene discussed is ALK; the disease is anaplastic large cell lymphoma.