After 60 days of infection, CD8+ T-cells expressing CCR5 decreased in the blood and MLN, particularly the population of CXCR3+CCR5+ CD8+ T-cells (Student’s t-test: blood, p = 0.004; MLN, p = 0.045) (Figure 4B and additional file: Table S3). Here, CXCR3 is linked to infection.