In this study, the effect size and ANOVA analyses on the influence of the 14 SNPs on the neurobehavioral vulnerability to TSD evidenced the possible influence of the two other pro-inflammatory cytokines, IL1-β and IL-6, notably, the IL-6 SNP significant effect on PVT lapses and speed, Go/noGo commission errors, and KSS score. The gene discussed is IL1B; the disease is Tay-Sachs disease.