For example, the high expression of C-X-C motif chemokine ligand 10 (CXCL10), a chemokine that extensively contributes to atherosclerosis and coronary artery disease in endothelial cells, is driven in part by PRMT5 methylation of NF-κB at R30 and R35. This evidence concerns the gene CXCL10 and coronary artery disorder.