Mahat et al. in their review and meta-analysis concluded that in patients with severe COVID-19, serum levels of CRP, ESR, PCT (procalcitonin), IL-6, IL-10, IL-2R, ferritin, SAA (serum amyloid A) and NLR (neutrophil-to-lymphocyte ratio) are significantly increased compared with people with a mild COVID-19. The gene discussed is IL10; the disease is COVID-19.