A study accomplished by A TransAtlantic Cardiovascular Consortium for Rheumatoid Arthritis (ATACC-RA) discovered that approximately 49% of CV incidents in RA were caused by traditional CVD risk factors (especially smoking and hypertension) and 30% by RA-related aspects, such as elevated DAS (Disease Activity Score) 28, positive rheumatoid factor (RF) and/or anti-citrullinated protein antibody (ACPA), and raised erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) [12]. This evidence concerns the gene CRP and hypertensive disorder.