HLA-DRB1 and COVID-19: Although DRB1* alleles were not reported in Nguyen et al. as potentially associated with severe COVID-19 based on binding affinity, the HLA-DRB1*08 allele has been associated with the highest risk for severe disease in a Sardinian population [12] as well as with mortality in an Italian cohort of patients [13] while Novelli et al. reported a significant association of disease severity with HLA-DRB1*15:01.