Specifically, the HLA-DRB1*01 allele was shown to have an increased frequency in COVID-19 patients compared to healthy controls (Table 4) The specific allele was also found increased in both mild and hospitalized patients compared to healthy controls (Table 5) and also maintained significance following Bonferroni correction in the mild group suggesting that it may potentially act as a genetic predisposition factor for SARS-CoV-2 infection. This evidence concerns the gene HLA-DRB1 and COVID-19.