EGFR and breast carcinoma: As displayed in Figure 15, Song et al. synthesized CDs coupled with bimetallic CuCo Prussian blue analogue (CD@CuCo PBA), and used it as gold electrode modifier to develop an electrochemical aptasensor for the detection of an epidermal growth factor receptor (EGFR) and EGFR-overexpressed MCF-7 breast cancer cells [230].