Studies had shown that GPS (2.973 g/kg for 4 weeks, i.g.)might enhance the level of autophagy of AS model mice by regulating the mTOR/unc-51-like kinase 1 (ULK1) autophagy signaling pathway, alleviate the formation of atherosclerotic plaque, and prevent atherosclerosis [53]. Here, ULK1 is linked to atherosclerosis.