The neuroprotective and anti-neuroinflammatory role of BRB evaluated in a Parkinson’s disease mice model treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) showed that the BRB treatment induces enhanced autography, which promotes the autophagic degradation of NLRP3 and inhibits NLRP3 inflammasome activation, thus mitigating neurotoxicity [61]. Here, NLRP3 is linked to Parkinson disease.