TAMs favor a protumor microenvironment, being related to facilitating the infiltration of GBM cells in the brain and, additionally, to inducing tumor neovascularization by producing pro-angiogenic factors such as CXC-chemokine ligand 2 (CXCL2) and vascular endothelial growth factor (VEGF) [31,37,38]. Here, VEGFA is linked to glioblastoma.