Expression levels of selected genes in skeletal muscle are shown in Figure 6C. Compared with NF and HF controls, MET and BC+MET mice had highly increased muscle expression levels of genes for proteins involved in fatty acid extraction from triglycerides of circulating lipoproteins (Lpl), cellular and mitochondrial uptake of fatty acids (Cd36), mitochondrial fatty acid oxidation (Cpt1b, Mcad, Ucp3) and basal glucose uptake (Slc2a1). The gene discussed is SLC2A1; the disease is breast cancer.