Unlike in our previous study [12], in this work, we did not observe downregulation of Pparg expression in WAT depots following treatment with BC alone, yet there are multiple differences between the two studies, including not only dosage, formulation and duration of the BC treatment, but, most importantly the type of diet, which was a normal-fat diet in the previous study and a high-fat diet in the present one. This evidence concerns the gene PPARG and breast cancer.