INS and obesity due to melanocortin 4 receptor deficiency: Further, 57 days of high-amylose maize supplementation also decreased fasting (22%, p = 0.04), 2 h postprandial (23.3%, p < 0.008), and 3 h postprandial (18.9%, p = 0.05) plasma insulin and improved HOMA-IR (23.1%, p = 0.04) in individuals with overweight/obesity with an increased risk for type 2 diabetes [42].