IL6 and type 2 diabetes mellitus: However, it has been shown that in obese children and patients with T2DM, acute exercise can induce a worsening in inflammation and OS; indeed, IL-6 levels, elevated under basal conditions in comparison to controls, further increased after exercise in T2DM, while myeloperoxidase, which was basally increased in T2DM, showed an exercise-induced increment in obese children.