MFN2 and hydrops fetalis: Maternal HF diet increased mRNA expression of Mfn2 in PND21 female and adult male/female offspring (main effect of maternal HF diet, p < 0.05, Figure 4B–D), while maternal metformin just decreased Mfn2 expression in adult males and females (main effect of maternal metformin, p < 0.05, Figure 4C,D).