In the HFD-induced obesity group, we noticed a marked reduction in the total expression of GLUT1 (−56.7%, p < 0.05, vs. control group; Figure 6E) as well as a significant decline in the HFD+ALA group (−49.1%, p < 0.05, vs. control group; Figure 6E). The gene discussed is SLC2A1; the disease is obesity due to melanocortin 4 receptor deficiency.