INS and metabolic syndrome: As reported in Table 2, the beneficial effects of the more frequent medical supervision and, consequently, of the more relevant weight loss in the responsive group were demonstrated by significant changes in auxometric and cardiometabolic parameters such as WC, HC, FM, FFM, HDL-C, LDL-C, TG, glucose, insulin, HOMA-IR and IDF criteria for the diagnosis of metabolic syndrome when compared with the stable and non-responsive groups (p < 0.05).