KRT14 and cancer: Mouse models based on the Krt14 gene promoter (K14-HPV16 mice) are well characterized, reliable and are an important for studying HPV16-induced lesions, as previously reviewed [25,32], the role of HPV16 oncogenes [14,15] the influence of co-carcinogens [21,22,23,24] and immune evasion mechanisms [27,33], as well as cancer chemopreventive strategies [26,28,34].