VEGFA and cancer: In this study, ivermectin-2VPFs in 0–100 ns, Gly59, His86, Gln87, Leu32, Asp34, Phe36, Gln37, Ser50, Cys57, Cys68, Glu73 and His99 residues have a key part in the strong hydrogen interactions that are located in the interaction pocket of VEGF proteins expressing in cancer cells.