AFP and classic galactosemia: Patients with NICCD generally suffer from prolonged jaundice, failure to thrive, hepatomegaly, diffuse fatty liver, parenchymal cellular infiltration associated with hepatic fibrosis, variable liver dysfunction, hypoproteinemia, coagulopathy, hemolytic anemia, elevated alpha-fetoprotein level, hypoglycemia, multi-aminoacidemia (citrulline, arginine, threonine, methionine, tyrosine, and elevated threonine/serine ratio), and galactosemia before 1 year old [12].