Leukosomes are able to target cancer vasculature, due to the presence of the leukocyte membrane proteins responsible for cellular adhesion, such as Lymphocyte Function-associated Antigen 1 (LFA-1), Macrophage-1 antigen (Mac-1) and P-Selectin Glycoprotein Ligand-1 (PSGL-1). This evidence concerns the gene SELPLG and cancer.