In a case-control study conducted in Brazil, (161 cases and 257 controls), women with no HPV-associated cancer harboring the alleles DRB1*1503, DRB1*0405 and DQB1*0602 were more likely to have an HPV positive test [27] and another study conducted in Mexico (172 women) observed that the allele HLA-DRB1*07 was associated with viral clearance. Here, HLA-DRB1 is linked to cancer.