Thus, numerous genetic polymorphisms in immune response genes, including IL-1 [48], IL-10 [49], IL-17 [50], toll-like receptor (TLRs) [51], interferon-gamma (IFN-γ) [52], tumor necrosis factor-alpha (TNF-α) [49,53,54,55] and a variety of genes [55,56,57] have been reported in association with cervical cancer susceptibility, however, inconsistent results are frequently found and most of these findings have not been replicated in larger cohorts. The gene discussed is TNF; the disease is cervical carcinoma.