HLA-DRB1 and myeloid sarcoma: However, a study comprising 285 Caucasian patients with MS (from Russia) evaluated the effect of nine polymorphisms in genes that coded for important pro- and anti-inflammatory cytokines (TNF, IFNG, TGFB1, IFNB1), cytokine receptors (IFNAR1, IL7RA, CCR5), CTLA4, and DRB1.