NEU1 and influenza: For example, oseltamivir phosphate, an extensively used anti-influenza drug and a viral sialidase inhibitor, targets human NEU1 showing encouraging results in preventing tumor cell metastasis [76,77] The inhibition of NEU1 expression by oseltamivir phosphate leads to overexpression of E-cadherin and downregulation of N-cadherin expression, which may limit the ability of cells to metastasize and increase their sensitivity of antineoplastic drugs [78].