FOXD4 and cancer: Among the 142 genes associated with poor survival composing the RNA-seq-based risk score, we found seven genes (ATP8B1, FGFR4, FOXD4, MX1, NPTXR, TMEM171, and TNFRSF10B) with a significantly lower DEMETER2 score in the myeloma cell lines (n = 16) compared to other cancer cell lines (n = 695) (Figure 4A and Table 4).