Using the HMDD, seven MTI (hsa-miR-193b–APP, hsa-miR-29c–BACE1, hsa-miR-613–BDNF, hsa-miR-29c–DNMT3, hsa-miR-206–IGF1, hsa-miR-128–PPARG, and hsa-miR-146a–TLR2) were observed in the body fluids of AD patients. This evidence concerns the gene APP and Alzheimer disease.