Moreover, the multivariate model revealed that the polymorphism of INSIG2 rs11123469 (T/C) was found to be significantly associated with hypertriglyceridemia after adjustment for the multivariate analyses (odds ratio = 0.37, 95% confidence interval = 0.14–0.97, p = 0.043). This evidence concerns the gene INSIG2 and hypertriglyceridemia.