One study used 2-(1-(6-[(2-[F-18]fluoroethyl)(methyl)amino]-2naphthyl)ethylidene)malononitrile (FDDNP)-PET, which is a technique that allows analysis of βA plaques and Tau tangles deposition in brain, showing that higher consume of MD is related with lower FDDNP-PET binding, both in MCI and subjective memory impairment participants [33]. This evidence concerns the gene MAPT and memory impairment.