In our study, patients with CPA were suggested to have hypoxia-associated angiogenesis, and the chemokine VEGFA was slightly associated with skewness (r2 = 0.07, p = 0.08) and kurtosis (r2 = 0.08, p = 0.07) in the univariate analysis (data not shown). Here, VEGFA is linked to congenital primary aphakia.